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DNA synthesis in Escherichia coli during a nutritional shift-up
Abstract:
DNA synthesis in a thymine-requiring Escherichia coli K12 strain was studied by exploiting deoxyguanosine, so simulating the behaviour of Thy+ strains. DNA synthesis is inhibited during the first 24 min after a nutritional shift-up. The new DNA/mass is lower than that predicted by current models for initiation control.