Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Upper eyelid retraction and Graves' disease

A S Grove

    Ophthalmology
    |June 1, 1981
    PubMed
    Summary

    Graves' disease can cause eyelid retraction. Levator marginal myotomy surgery effectively treats this by addressing levator muscle abnormalities, improving eyelid position in patients.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A piece of my mind. The X Factor.

    JAMA·1998
    Same author

    The multidisciplinary management of psammomatoid ossifying fibroma of the orbit.

    Ophthalmology·1998
    Same author

    The role of the integrin family of adhesion molecules in the development of tumors metastatic to the orbit.

    Ophthalmic plastic and reconstructive surgery·1998
    Same author

    Orbital and eyelid manifestations of neurofibromatosis: a clinical study and literature review.

    Ophthalmic plastic and reconstructive surgery·1996
    Same author

    Ocular adnexal lymphoma. A clinicopathologic study with identification of lymphomas of mucosa-associated lymphoid tissue type.

    Ophthalmology·1995
    Same author

    Merkel cell carcinoma of the eyelid and periocular tissues.

    American journal of ophthalmology·1992

    Area of Science:

    • Ophthalmology
    • Endocrinology
    • Surgical Pathology

    Background:

    • Graves' disease is an autoimmune disorder frequently associated with thyroid eye disease.
    • Eyelid retraction is a common and visually impairing manifestation of thyroid eye disease.
    • Abnormalities in the levator muscle contribute significantly to eyelid retraction in Graves' ophthalmopathy.

    Purpose of the Study:

    • To evaluate the efficacy of levator marginal myotomy for correcting eyelid retraction in Graves' disease.
    • To describe the surgical technique for levator marginal myotomy.
    • To correlate clinical and histological findings in patients with Graves' disease and eyelid retraction.

    Main Methods:

    • Surgical treatment involving levator marginal myotomy was performed on ten upper eyelids.
    • Clinical examination documented the presentation of eyelid retraction.
    • Histopathological analysis examined levator muscle, orbicularis muscle, and orbital septum tissues.

    Main Results:

    • The most frequent clinical findings included levator muscle thickening, fatty infiltration, and adhesions.
    • Histologic examination revealed significant collagen proliferation, striated muscle atrophy, and fatty infiltration.
    • Levator marginal myotomy was utilized as the surgical intervention.

    Conclusions:

    • Levator marginal myotomy is a useful surgical technique for managing eyelid retraction in Graves' disease.
    • Understanding the histopathological changes in the levator muscle is crucial for surgical planning.
    • The study describes the technique and demonstrates the usefulness of this surgical approach.

    Related Experiment Videos