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Hypercalcaemia--a hospital survey

R A Fisken, D A Heath, A M Bold

    The Quarterly Journal of Medicine
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    This study investigated hypercalcaemia prevalence and causes in hospital patients. Malignancy was the most common cause, followed by chronic renal failure and primary hyperparathyroidism.

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    Area of Science:

    • Endocrinology
    • Nephrology
    • Oncology

    Background:

    • Hypercalcaemia, elevated serum calcium, is a common metabolic disturbance.
    • Identifying the underlying causes of hypercalcaemia is crucial for patient management.

    Purpose of the Study:

    • To determine the prevalence of hypercalcaemia in hospital inpatients.
    • To identify the primary causes of genuine hypercalcaemia.

    Main Methods:

    • Retrospective survey of hospital inpatients with elevated serum calcium.
    • Exclusion of spurious measurements.
    • Analysis of 469 confirmed cases of hypercalcaemia.

    Main Results:

    • Malignancy was the leading cause of hypercalcaemia (219 cases).

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  • Chronic renal failure (68 cases) and primary hyperparathyroidism (59 cases) were other significant causes.
  • In 102 cases, no specific cause for hypercalcaemia was identified.

    • Conclusions:

    • Malignancy is a predominant cause of hypercalcaemia in hospitalized patients.
    • Chronic renal failure and primary hyperparathyroidism are also common contributors.
    • Further investigation is needed for unexplained hypercalcaemia cases.