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Related Experiment Videos

Polymicrobial endocarditis involving Eikenella corrodens

J D Sobel, J Carrizosa, T F Ziobrowski

    The American Journal of the Medical Sciences
    |July 1, 1981
    PubMed
    Summary

    Eikenella corrodens is a key cause of polymicrobial endocarditis in parenteral amphetamine abusers. Early recognition and management are crucial for this serious infection.

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    Area of Science:

    • Infectious Diseases
    • Cardiology
    • Microbiology

    Background:

    • Endocarditis is a serious infection of the heart's inner lining.
    • Parenteral amphetamine abuse is a known risk factor for infectious endocarditis.
    • Polymicrobial endocarditis involves multiple types of microorganisms.

    Observation:

    • Two cases of endocarditis in amphetamine abusers involving Eikenella corrodens are presented.
    • Case 1: A 26-year-old woman with left-sided endocarditis due to S. aureus and Eikenella corrodens developed severe mitral regurgitation.
    • Case 2: A 29-year-old man with right-sided endocarditis had three organisms isolated, including Eikenella corrodens.

    Findings:

    • This is the first report detailing polymicrobial endocarditis with Eikenella corrodens.

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  • Eikenella corrodens plays a significant role in endocarditis among parenteral amphetamine users.
  • Diagnosis and management of Eikenella-associated valve infections present unique challenges.
  • Implications:

    • Highlights the importance of considering Eikenella corrodens in endocarditis, especially in intravenous drug users.
    • Underscores diagnostic and therapeutic difficulties associated with polymicrobial Eikenella infections.
    • Emphasizes the need for vigilance in recognizing and treating Eikenella endocarditis in at-risk populations.