Calcium and calmodulin in the regulation of blood cell functions (a mini-review)

A great deal of cellular functions are regulated by changes in intracellular calcium concentration. Calmodulin, a low molecular weight cytoplasmic protein is basically involved in this regulation through a calcium-dependent interaction with various enzyme systems. The review discusses the chemical and physiological basis of calcium and calmodulin actions in the cell interior. Describes calcium-regulation of various functions in red cells, platelets and leukocytes.