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Urticarial vasculitis: an updated review

E W Monroe

    Journal of the American Academy of Dermatology
    |July 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Urticarial vasculitis presents as hives but shows necrotizing vasculitis on biopsy, likely due to immune complex deposition. This review explores its clinical, lab, and immunopathologic features.

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    Area of Science:

    • Dermatology
    • Immunopathology

    Background:

    • Urticaria and vasculitis are distinct skin reactions with varied causes.
    • Urticarial vasculitis is a recently identified condition.
    • It combines urticarial presentation with vasculitic biopsy findings.

    Purpose of the Study:

    • To analyze clinical, laboratory, and immunopathologic features of urticarial vasculitis.
    • To define the concept of urticarial vasculitis.

    Main Methods:

    • Review of isolated cases of urticarial vasculitis.
    • Analysis of skin biopsy findings (necrotizing vasculitis).
    • Examination of clinical, laboratory, and immunopathologic data.

    Main Results:

    • Urticarial vasculitis presents clinically as urticaria.

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  • Skin biopsies reveal necrotizing vasculitis.
  • Immune complex deposition is the probable pathogenic mechanism.

    • Conclusions:

    • Urticarial vasculitis represents a specific reaction pattern.
    • Understanding its features is crucial for diagnosis and management.
    • Further research into immune complex-mediated mechanisms is warranted.