A method for short- and long-term in vivo study of the bone-implant interface

A screw-shaped titanium chamber has been designed for serial in vivo observations of the bone-implant interface. First, the chamber is implanted; later a test substance, e.g. bone cement, is inserted in the chamber and brought in contact with the bone with minimal trauma. Both acute and long-term effects can be intravitally observed, photographed, and recorded.