Related Experiment Video

Updated: Sep 13, 2026

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

Coronary angiogram interpretation. Interobserver variability

J E Galbraith, M L Murphy, N de Soyza

    JAMA
    |November 3, 1978
    PubMed

    Insights

    This study assessed coronary angiogram interpretation accuracy by comparing clinical readings with postmortem data. While generally accurate, a majority opinion did not always resolve discrepancies, indicating interpretation limitations.

    Area of Science:

    • Cardiology
    • Pathology
    • Medical Imaging

    Background:

    • Coronary angiography is a key diagnostic tool for coronary artery disease.
    • Interobserver variability in interpreting angiograms can affect clinical decisions.
    • Pathological findings serve as the gold standard for accuracy.

    Purpose of the Study:

    • To determine interobserver variability in coronary angiogram interpretation.
    • To correlate premortem coronary angiograms with postmortem data.
    • To assess the accuracy of clinical interpretations against pathological findings.

    Main Methods:

    • Three cardiologists independently interpreted coronary angiograms.
    • Interpretations were compared with postmortem pathological data.
    • Diagnostic accuracy and interobserver agreement were analyzed.

    Main Results:

    • No substantial difference in overall diagnostic accuracy was found among the three cardiologists.
    • Most substantial angiographic lesions were pathologically verified.
    • Majority opinions accurately identified pathological lesions in 50% of false-positive/negative interpretations.

    Conclusions:

    • Coronary angiography is an excellent diagnostic tool.
    • Limitations in interpretation accuracy persist, even with majority opinion.
    • Pathological correlation is crucial for validating angiographic findings.

    More Related Videos

    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression13:07

    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

    Published on: January 15, 2022

    Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography07:18

    Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

    Published on: February 18, 2022

    Related Concept Videos

    Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

    Radiological Investigation III: Pulmonary Angiogram and PET Scan

    Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
    Pulmonary Angiogram
    A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
    Imaging Studies for Cardiovascular System I:Echocardiography01:17

    Imaging Studies for Cardiovascular System I:Echocardiography

    Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
    Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
    Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

    Imaging Studies for Cardiovascular System II:Types of Echocardiography

    Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
    Types of Echocardiography
    Transthoracic Echocardiography (TTE)
    TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
    Imaging Studies for Cardiovascular System IV: CMRI01:21

    Imaging Studies for Cardiovascular System IV: CMRI

    Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
    Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

    Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

    Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
    Acute Coronary Syndrome III: Diagnostic Studies01:30

    Acute Coronary Syndrome III: Diagnostic Studies

    Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...