Genetic polymorphism of plasminogen: a new basic variant (PLG B) and population study in Japanese

Genetic polymorphism of human plasminogen in the Japanese population was studied using agarose gel isoelectric focusing followed by immunofixation. A new basic variant, PLG B, was found as a heterozygous state PLG 1-B, which was genetically determined. The allele frequencies calculated from 258 individuals were PLG1=0.958, PLG2=0.020 and PLGB=0.022.