Papilledema in Behçet's syndrome

Area of Science:

• Neurology
• Rheumatology
• Vascular Medicine

Background:

• Behçet's syndrome is a rare multisystem inflammatory disorder.
• Intracranial hypertension is not a commonly recognized initial manifestation.

Observation:

• Six patients with Behçet's syndrome presented with intracranial hypertension.
• Symptoms included headaches and papilledema with normal or small ventricles.

Findings:

• Cerebral vein thrombosis was identified as the cause of intracranial hypertension in these patients.
• Associated symptoms included oral ulcers, genital ulcers, uveitis, arthralgia, and thrombophlebitis.

Implications:

• Papilledema and intracranial hypertension due to cerebral vein thrombosis may be early indicators of Behçet's syndrome.
• This highlights the need for increased awareness among clinicians regarding neurological manifestations of Behçet's syndrome.