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Updated: Aug 8, 2026

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
Published on: May 6, 2013
[Islet cell antibodies in diabetic patients with other autoimmune diseases (author's transl)]
Abstract:
The presence of antibodies directed against pancreatic islet cells was investigated in 18 insulin pendent diabetic patients with autoimmune disease (Group 1), in 8 insulin-independent diabetic patients with autoimmune disease (Group 2), in 42 non-diabetic patients with thyroid antibodies (Group 3), in 18 patients with antibodies against gastric parietal cells (Group 4) and in 100 healthy subjects (controls). Islet cell antibodies were found in 46% of group 1 patients and in only 1 patient of group 3 and 1 control. This would suggest the existence of a special form of autoimmune insulin-dependent diabetes characterized by a high incidence of islet cell antibodies and associated with other autoimmune diseases.
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