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[Human cutaneous alternariosis. 3 cases. Review of the literature (author's transl)]
Annales De Dermatologie Et De Venereologie
|January 1, 1981
Abstract:
The authors present 3 new cases of dermal alternariosis, associated with one Hodgkin's disease and 2 kidney transplants. Review of the other cases of literature demonstrates the pathogenicity of this saprophytic fungus which becomes opportunistic mostly in case of immuno-deficiency. Clinical aspect is usually that of papulo-nodular, ulcerative or vegetating, unique or multiple lesions of limbs and head. Its course is very capricious, not infrequently chronic and extensive. The treatment is not yet well established.
Insights
Dermal alternariosis, a fungal infection, can occur in immunocompromised patients, such as those with Hodgkin
Area of Science:
- Mycology
- Dermatology
- Immunology
Background:
- Alternaria species are ubiquitous saprophytic fungi.
- Dermal alternariosis is a rare fungal infection.
- Opportunistic infections are common in immunocompromised individuals.
Observation:
- Three new cases of dermal alternariosis are presented.
- Cases were associated with Hodgkin's disease and kidney transplants.
- Clinical presentations included papulo-nodular, ulcerative, and vegetating lesions on limbs and head.
Findings:
- Alternaria species demonstrate pathogenicity in immunocompromised hosts.
- The fungus acts as an opportunistic pathogen, particularly in states of immunodeficiency.
- The clinical course is variable, often chronic and extensive.
Implications:
- Highlights the potential of saprophytic fungi to cause opportunistic infections.
- Underscores the importance of considering fungal infections in immunocompromised patients with skin lesions.
- Emphasizes the need for further research into effective treatment strategies for dermal alternariosis.