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[Tumor field]

V A Rykov

    Arkhiv Patologii
    |January 1, 1981
    PubMed
    Summary

    The tumor field concept of Willis requires further investigation. Evidence supports its role in understanding tumor genesis and development, necessitating deeper studies into neoplasia morphogenesis.

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    Area of Science:

    • Oncology
    • Developmental Biology
    • Pathology

    Context:

    • The concept of the tumor field of Willis proposes a specific framework for understanding tumor development.
    • Existing literature presents both supporting ('pro') and opposing ('contra') data regarding this concept.

    Purpose:

    • To review and present literature data concerning the tumor field of Willis concept.
    • To highlight the implications of this concept for understanding tumor genesis and morphogenesis.

    Summary:

    • The presented data, drawn from existing literature, evaluates arguments for and against the tumor field of Willis concept.
    • Examples illustrate how formal genesis regularities of certain tumors align with the tumor field concept.
    • This alignment suggests the concept's potential utility in explaining neoplastic development.

    Impact:

    • The review underscores the necessity for continued research into the histo- and morphogenesis of neoplasia.
    • Adopting the tumor field concept's perspective may offer novel insights into cancer development and progression.
    • Further studies are crucial to validate and refine the application of the tumor field concept in oncology.

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