Direct immunofluorescence on cytological smears in oral pemphigus

Direct immunofluorescence was performed on washed oral epithelial smears from thirteen patients with pemphigus vulgaris, thirteen patients with other oral diseases and from ten subjects with clinically healthy oral mucosa. The intercellular deposition of IgG was observed on cytological smears from oral smears from oral lesions in all patients with other oral diseases and from healthy controls, did not show any fluorescence. Therefore, direct immunofluorescence on cytological smears may be of value in the diagnosis of pemphigus.