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Factors affecting the bioavailability of zinc
Journal of the American Dietetic Association
|February 1, 1982
Summary
Individual zinc absorption depends on host and dietary factors, with intestinal regulation playing a key role. Researchers aim to identify dietary components that influence zinc bioavailability.
Area of Science:
- Human Nutrition
- Gastroenterology
- Mineral Metabolism
Background:
- Zinc absorption is influenced by host nutritional status and intestinal factors.
- Gastrointestinal diseases can impair zinc absorption efficiency.
- Dietary zinc bioavailability varies, with higher availability from animal-based foods and breast milk.
Purpose of the Study:
- To elucidate the mechanisms of normal dietary zinc absorption in humans.
- To identify specific foods and chemical compounds that modulate zinc absorption.
Main Methods:
- Review of existing literature on zinc absorption.
- Analysis of factors influencing zinc bioavailability from different food sources.
- Identification of host and dietary determinants of zinc uptake.
Main Results:
- Intestinal mucosa regulates zinc entry based on host zinc nutriture.
- Impaired digestion, zinc-binding ligand secretion, or absorption processes reduce zinc uptake.
- Breast milk and animal-derived foods generally offer greater zinc availability than cow's milk or plant-based foods.
Conclusions:
- Understanding the complex mechanisms of zinc absorption is crucial for nutritional science.
- Further research is needed to identify dietary strategies for optimizing zinc status.