[Sensitivity to insulin in thyrotoxicosis]

Insulin and glucose-insulin sensitivity of peripheral tissues is studies in patients with thyrotoxicosis of different severity and duration. Three main types of the curves, characterizing exogenic insulin sensitivity, were detected. It was determined that a decrease in insulin sensitivity and insulin resistance prevailed in patients with disturbed glucose tolerance (the doubtful type of glycemic curve, latent diabetes). The results obtained do not eliminate the significance of insulin sensitivity failure in the affection of adaptive characteristics of the pancreatic insulin-producing apparatus in thyrotoxicosis.