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[Observation on the course of arterial hypertension after kidney transplantation]
Insights
Blood pressure improved after kidney transplantation, with hypertension reducing from 66% to 50% of patients. Glomerulonephritis patients showed persistently high hypertension rates, suggesting specific management needs post-transplant.
Area of Science:
- Nephrology
- Cardiovascular Medicine
- Transplantation Science
Context:
- Investigated blood pressure in 65 kidney transplant recipients over 18.6 months.
- Assessed hypertension prevalence before and after transplantation.
- Examined correlations with renal function, rejection, medications, and comorbidities.
Purpose:
- To analyze blood pressure behavior post-kidney transplantation.
- To identify factors influencing hypertension in transplant patients.
- To understand hypertension in the context of specific original renal diseases.
Summary:
- Hypertension decreased from 66% pre-transplant to 50% post-transplant.
- No significant correlation found between blood pressure and renal function, rejection, prednisolone dose, diabetes, or UTIs.
- Patients with glomerulonephritis showed a higher incidence of hypertension both before and after transplantation.
Impact:
- Highlights the reduction in hypertension post-transplant.
- Identifies glomerulonephritis as a risk factor for persistent hypertension.
- Suggests further investigation into hypertension causes like transplant arterial stenosis.
Abstract:
The behavior of blood pressure was investigated in 65 transplantation (Tx) patients in a nephrological outpatient service for an average of 18.6 months after Tx. Before Tx 2/3 of the patients exhibited hypertension, after Tx this was reduced to 1/2. No correlation was found between behaviour of blood pressure and such factors as renal function, incidence of rejection episodes, prednisolonee dose, diabetes mellitus and urinary function, incidence of rejection episodes, prednisolon dose, diabetes mellitus and urinary tract infection of the Tx. Only in patients with glomerulonephritis as original renal disease there was in increased incidence of hypertension before and after Tx. Causes of hypertension are discussed and demonstrated in the case of Tx arterial stenosis.