Developments in the tracer measurement of gluconeogenesis and glycogenesis in vivo: an overview

In summary, recent developments in the continuing effort to accurately measure gluconeogenetic rates are presented in this symposium. Problems and assumptions are discussed. Mathematical methods that form a basis for further progress are also given. A direct application to the measurement of the gluconeogenetic component of glycogen formation is then described. A further application to the assessment of gluconeogenesis in the fetal component of the fetal-maternal system is discussed. Finally, the importance of tracer sampling and infusion sites in turnover measurement is treated in detail.