[Phagocytic activity of leukocytes in acutely intoxicated persons]

Evaluation of the reaction of leukocytes in peripheral blood of people suffering from acute exogenic intoxications was undertaken. The examination comprised 47 persons aged 15--72, intoxicated with soporifics, sedatives, carbon monoxide and other substances (ethanol, methanol, lyes). The control group consisted of 26 persons, aged 18--56, in this 10 healthy persons, 10 persons with acute bacterial infections and 6 with viral infections. For evaluation of phagocytic activity of granulocytes a test of the reduction of nitrotetrazoline blue (NBT) was used. Besides the activity of non-specific esterases in monocytes and lymphocytes was determined. The data obtained demonstrated significant differences in the behaviour of the NBT test in granulocytes of acutely intoxicated persons, as compared with healthy people and those suffering from bacterial and viral diseases.