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[Small airways disease (author's transl)]

C Préfaut, P T Macklem

    Revue Francaise Des Maladies Respiratoires
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Small airways disease involves bronchial inflammation and arterial lesions, progressing to emphysema. Forced expiratory volume in one second (FEVI) around age 40 offers the best prognostic value for smokers.

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    Area of Science:

    • Pulmonary Medicine
    • Respiratory Physiology
    • Pathology

    Context:

    • Small airways disease (SAD) is a significant contributor to respiratory impairment.
    • Early detection and understanding of SAD progression are crucial for managing lung health.
    • Smokers represent a key demographic for studying SAD due to their increased risk.

    Purpose:

    • To define small airways disease and its anatomical characteristics.
    • To explore the correlation between small airways disease morphology and lung function tests.
    • To identify sensitive and specific tests for early detection and prognostic value in smokers.

    Summary:

    • Small airways disease is characterized by early bronchial inflammation and arterial lesions, progressing to vascular alterations and emphysema.

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  • Existing studies suggest a link between SAD and abnormal respiratory function tests.
  • For smokers, forced expiratory volume in one second (FEVI) measured around age 40 appears to have the highest prognostic value, rather than early screening.

    • Impact:

    • Highlights the prognostic significance of FEVI for smokers.
    • Suggests that early screening for SAD may be less critical than identifying individuals at risk of future decline.
    • Underscores the need for further research to validate early screening protocols and understand SAD consequences.