Mutagenic activity of caffeinated and decaffeinated coffee

Two types of coffee (caffeinated and decaffeinated) were tested for their mutagenicity using bacterial strains using TA98 and TA100 in Ames Salmonella/Microsome test. According to the Ames criteria, both were found to be mutagenic in the absence of S-9. The mutagens did not require liver enzymes to be activated.