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[Renal changes in malaria]

A Chianta, L Chiono, E Profumo

    Archivio Per Le Scienze Mediche
    |October 1, 1981
    PubMed
    Summary

    Malaria cases are rising globally, leading to increased renal complications. Plasmodium malariae causes nephrotic syndrome, while Plasmodium falciparum can lead to acute kidney injury or glomerulonephritis.

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    Area of Science:

    • Nephrology
    • Infectious Diseases
    • Tropical Medicine

    Background:

    • Global malaria cases and associated renal complications are increasing.
    • Plasmodium parasites are the causative agents of malaria.
    • Renal involvement in malaria requires careful examination due to rising incidence.

    Observation:

    • Plasmodium malariae can induce nephrotic syndrome.
    • Plasmodium falciparum is linked to acute renal insufficiency (functional or organic) and glomerulonephritis.
    • Glomerulonephritis in falciparum malaria is often acute and transient, but can progress.

    Findings:

    • The study reviews physiopathological mechanisms of malaria-induced renal syndromes.
    • Plasmodium falciparum can cause acute renal functional insufficiency.
    • Case study details acute renal functional insufficiency in a patient with Plasmodium falciparum malaria.

    Implications:

    • Understanding these renal complications is crucial for managing malaria patients.
    • Early diagnosis and treatment of renal issues in malaria can prevent severe outcomes.
    • Further research into the pathogenesis of malaria nephropathies is warranted.

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