[Undifferentiated carcinoma with lymphoid stroma (undifferentiated carcinoma nasopharyngeal type?). Optical, electron...

A case of undifferentiated carcinoma with lymphoid stroma of the paired gland is reported in a chinese woman with positive Epstein-Barr virus serology. The histologic appearance of the tumor is very similar to undifferentiated carcinomas nasopharyngeal type (UCNT). Ultrastructural study reveals features of epidermoid differentiation. Immunofluorescence study shows numerous and predominant IgA plasma cells in the stroma. The relationship between this tumor and the benign lymphoepithelial lesions of the salivary glands are discussed. The present case and the review of the literature emphasize the morphological and epidemiological similarities between UCNT and undifferentiated carcinoma with lymphoid stroma of the salivary glands.