Indoprofen. Short-term double-blind cross-over study in patients with osteoarthritis of the hip

A comparison was made between indoprofen (800 mg/day), naproxen (500 mg/day) and placebo in 30 patients with well defined osteoarthritis of the hip. Treatments were given for 10 days each, according to a double-blind, cross-over design. Objective and subjective criteria were adopted for evaluation of effectiveness. Special attention was paid to side effects. There was a marked difference between the active drugs and placebo. Indoprofen was significantly better than naproxen on many variables, and was, in most cases, preferred to the latter, by patients and investigator.