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Renal transplantation in leprosy
Summary
Tuberculoid leprosy patients can undergo successful renal transplantation. Continued healing of leprosy was observed despite immunosuppression, indicating it is not a contraindication.
Area of Science:
- Nephrology
- Dermatology
- Immunology
Background:
- Tuberculoid leprosy is a chronic infectious disease.
- Chronic renal failure necessitates renal replacement therapy.
- Renal transplantation is a treatment option for end-stage renal disease.
Observation:
- A patient with tuberculoid leprosy and chronic renal failure received a renal allograft.
- The patient had undergone 5 months of dapsone treatment prior to transplantation.
- Immunosuppression was administered post-transplantation.
Findings:
- Leprosy showed continued healing during immunosuppressive therapy.
- The patient's leprosy did not cause significant morbidity post-transplantation.
- Tuberculoid leprosy did not complicate the renal allograft outcome.
Implications:
- Tuberculoid leprosy is not a contraindication for renal transplantation.
- Successful renal allografting is feasible in patients with tuberculoid leprosy.
- This case highlights the management of co-existing leprosy and renal failure.