Modulation of basal insulin secretion in the obese, hyperglycemic mouse

Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations.

Diabetologia·2001

The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose.

Diabetes·2001

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance.

Cell·2001

Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice.

American journal of physiology. Endocrinology and metabolism·2001

The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function.

Diabetes·2001

Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.

Diabetes care·2001

Time-restricted eating, immunomodulation and ketone metabolism in humans.

Metabolism: clinical and experimental·2026

ASGR1 exacerbates MASLD by inducing hepatocyte senescence via lysosomal dysfunction and HIF-1α stabilization.

Metabolism: clinical and experimental·2026

Mesenchymal stem cell therapy for diabetes: clinical evidence, emerging strategies, and future perspectives.

Metabolism: clinical and experimental·2026

Multi-omics dissection of MASLD reveals divergent pathways to systemic diseases and targets for prevention.

Metabolism: clinical and experimental·2026

Alpha-ketoglutarate ameliorates diabetes-associated skeletal muscle fibrosis by restoring TET2-dependent epigenetic remodeling in CD90 positive fibro-adipogenic progenitors.

Metabolism: clinical and experimental·2026

HSF1-UCHL1 transcriptional axis protects against MASLD via regulation of PPARα protein stability.

Metabolism: clinical and experimental·2026

Emergence and molecular characterization of bovine alphaherpesvirus 1 subtype 1.1 in China, with in vivo characterization in a rabbit model.

Microbial pathogenesis·2026

Lipid droplet dynamics control type I interferon responses and viperin expression to suppress viral replication.

Veterinary microbiology·2026

Antigen-blocking phenomenon in dogs affected by Dirofilaria immitis: frequency, reversion, associated immune response and co-positivity with other vector-borne pathogens.

Veterinary parasitology·2026

Epidemiological study and risk factors of internal parasite infections in wild boar (Sus scrofa) in Mazandaran Province, northern Iran.

Parasite epidemiology and control·2026

Intestinal flagellin drives multisystem inflammation through TLR5-IL-15-ARA axis.

Gut·2026

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins.

Veterinary medicine and science·2026

Related Experiment Videos

Modulation of basal insulin secretion in the obese, hyperglycemic mouse

Related Concept Videos

Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations.

The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose.

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance.

Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice.

The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function.

Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.

Time-restricted eating, immunomodulation and ketone metabolism in humans.

ASGR1 exacerbates MASLD by inducing hepatocyte senescence via lysosomal dysfunction and HIF-1α stabilization.

Mesenchymal stem cell therapy for diabetes: clinical evidence, emerging strategies, and future perspectives.

Multi-omics dissection of MASLD reveals divergent pathways to systemic diseases and targets for prevention.

Alpha-ketoglutarate ameliorates diabetes-associated skeletal muscle fibrosis by restoring TET2-dependent epigenetic remodeling in CD90 positive fibro-adipogenic progenitors.

HSF1-UCHL1 transcriptional axis protects against MASLD via regulation of PPARα protein stability.

Emergence and molecular characterization of bovine alphaherpesvirus 1 subtype 1.1 in China, with in vivo characterization in a rabbit model.

Lipid droplet dynamics control type I interferon responses and viperin expression to suppress viral replication.

Antigen-blocking phenomenon in dogs affected by Dirofilaria immitis: frequency, reversion, associated immune response and co-positivity with other vector-borne pathogens.

Epidemiological study and risk factors of internal parasite infections in wild boar (Sus scrofa) in Mazandaran Province, northern Iran.

Intestinal flagellin drives multisystem inflammation through TLR5-IL-15-ARA axis.

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins.

Related Experiment Videos

Modulation of basal insulin secretion in the obese, hyperglycemic mouse

Related Concept Videos

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