Regulation of catalase biosynthesis in Saccharomyces cerevisiae: factor repressing catalase biosynthesis

A factor which represses the catalase biosynthesis in yeast has been demonstrated in Saccharomyces cerevisiae. This factor can be obtained from yeast cells having both low and normal catalase levels, and is unable to enter the intact cytoplasmic membrane. Moreover, the factor-containing cell extracts obtained either from acatalasemic mutants or normal strains grown in catalase repressive conditions showed higher activity than those obtained from normal strains after being cultured in permissive conditions.