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Updated: Aug 12, 2026

In vitro Functional Characterization of Mouse Colorectal Afferent Endings
Published on: January 21, 2015
[Ultrastructural changes in the nerve endings in the large intestine mucosa in Sonne dysentery]
Abstract:
Biopsies of the large intestine of patients with dysentery due to Shigella sonnei were examined. Electron microscopy examinations showed changes in nerve endings in the stroma of the mucous membrane to correlate with the intensity of general histopathological lesions in it. Changes in the nervous apparatus may be of reversible, structural-functional nature in mild cases of the disease or become irreversible in the structures providing transformation and transmission of the nervous signal in synaptic parts of neurites.
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