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Coagulative interventions during angiography

J J Bookstein, K M Moser, C Hougie

    Cardiovascular and Interventional Radiology
    |January 1, 1982
    PubMed
    Summary
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    Angiographers increasingly manage blood clotting during procedures. This review covers coagulation fundamentals, heparin, protamine sulfate, platelet function, and fibrinolytic therapy for interventional radiology.

    Area of Science:

    • Interventional Radiology
    • Hematology
    • Vascular Medicine

    Background:

    • Angiographers frequently encounter hemostasis management during diagnostic and interventional procedures.
    • Conventional angiographic training often does not cover the complexities of blood coagulation.
    • A growing need exists to understand and manage coagulation factors in interventional settings.

    Purpose of the Study:

    • To review the fundamentals of coagulation relevant to angiography.
    • To outline methods for manipulating coagulation during angiographic procedures.
    • To discuss the roles of antiplatelet and fibrinolytic agents in interventional radiology.

    Main Methods:

    • Review of coagulation and hemostasis principles.
    • Analysis of anticoagulant and antiplatelet agents (heparin, protamine sulfate, aspirin, dipyridamole).

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  • Examination of the fibrinolytic system and its therapeutic applications.

    • Main Results:

    • Coagulation involves complex interactions of clotting factors and platelets.
    • Heparin and protamine sulfate are key agents for modulating coagulation during angiography.
    • Aspirin and dipyridamole affect platelet activity, influencing bleeding risk.
    • Fibrinolytic therapy plays a role in managing thrombotic complications.

    Conclusions:

    • Understanding coagulation is crucial for safe and effective angiography.
    • Pharmacological manipulation of hemostasis is an integral part of interventional radiology.
    • Further research into tailored coagulation management in interventional procedures is warranted.