Idiopathic portal hypertension in a renal transplant recipient

A renal transplant recipient developed a noncirrhotic form of portal hypertension, idiopathic portal hypertension, several years after the transplantation. The liver histology by light microscopy disclosed only chronic portal inflammation and portal fibrosis; however, a prominent collagen deposition with the space of Disse seen only by electron microscopy evolved during the course of the liver disease. This report, in association with other reports of the same disorder in renal transplant recipients, suggests that idiopathic portal hypertension may occur as a direct consequence of renal transplantation.