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Tuberculosis affecting a cadaveric renal allograft

J F Walker, C J Cronin, S O'Neill

    Clinical Nephrology
    |May 1, 1982
    PubMed
    Summary
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    Tuberculosis can complicate kidney transplants, especially with higher prednisone doses. Successful treatment with chemotherapy was achieved in a case of renal allograft tuberculosis without impacting kidney function.

    Area of Science:

    • Nephrology
    • Infectious Diseases
    • Transplantation Immunology

    Background:

    • Tuberculosis (TB) is a serious infection that can occur after renal transplantation.
    • Higher doses of prednisone (>10 mg daily) are linked to more severe TB disease in transplant recipients.

    Observation:

    • A case of renal allograft tuberculosis with confirmed bacteriological and radiological evidence is presented.
    • The patient received successful anti-tuberculosis chemotherapy.

    Findings:

    • Treatment with anti-tuberculosis chemotherapy was effective in managing renal allograft tuberculosis.
    • No deterioration in renal function was observed post-treatment.

    Implications:

    • This case highlights the importance of considering TB in renal transplant recipients, particularly those on immunosuppression.

    Related Experiment Videos

  • Effective chemotherapy can successfully treat renal allograft TB without compromising graft function.
  • Prophylaxis strategies for TB-history patients undergoing transplantation warrant further discussion.