Interaction between human neutrophils and group B streptococci (GBS) and group antigens, monitored by...

Interaction between the five serotypes of GBS and human neutrophils was investigated using Luminol-dependent chemiluminescence. A considerable variation in response, and a variable dependence pre-opsonisation was demonstrated both for while bacteria and HCl-extracts. These preliminary results may have relevance to clinical infection with GBS and demonstrate hitherto unrecognised differences in the nature of "group-specific" antigen extracts from GBS serotypes.