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Related Experiment Videos

Changes in certain blood constituents during Ramadan

S S Fedail, D Murphy, S Y Salih

    The American Journal of Clinical Nutrition
    |August 1, 1982
    PubMed
    Summary

    Ramadan fasting significantly impacts key health markers, increasing serum cholesterol, thyroxine, and uric acid while decreasing body weight. These Ramadan-related changes in biochemical markers are important for physicians to consider.

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    Area of Science:

    • Endocrinology
    • Metabolic Medicine
    • Clinical Biochemistry

    Background:

    • Ramadan fasting involves prolonged periods without food or drink.
    • Fasting can influence various physiological and metabolic parameters.
    • Understanding these changes is crucial for clinical practice in Muslim populations.

    Purpose of the Study:

    • To investigate the effects of Ramadan fasting on specific serum biochemical markers.
    • To assess changes in lipid profiles, thyroid hormones, uric acid, gastrin, and insulin during Ramadan.
    • To inform healthcare providers about potential alterations in laboratory findings.

    Main Methods:

    • Prospective study involving 24 Muslim participants.
    • Fasting serum levels of cholesterol, triglycerides, thyroxine (T4), triiodothyronine (T3), uric acid, gastrin, and insulin were measured.

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  • Measurements were taken at the beginning and end of the Ramadan fasting month.

    • Main Results:

    • Significant increases observed in total serum cholesterol, thyroxine, and uric acid levels.
    • A significant decrease in mean body weight was noted.
    • No significant changes were found in serum triglycerides, triiodothyronine, fasting gastrin, fasting insulin, or postprandial responses of gastrin and insulin.

    Conclusions:

    • Ramadan fasting leads to significant alterations in specific biochemical markers, including increased cholesterol, thyroxine, and uric acid, and decreased body weight.
    • These biochemical changes, while minor for healthy individuals, could be clinically relevant for patients.
    • Physicians in Muslim-majority regions should be aware of these Ramadan-induced laboratory finding variations.