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Termination of early pregnancy by ONO-802 suppositories (16,16-dimethyl-trans-delta2-PGE1 methyl ester)
Prostaglandins
|May 1, 1978
Abstract:
ONO-802 was used in the form of vaginal suppositories for the termination of early pregnancy in 63 healthy volunteers. Fifty-four (86%) of the 63 cases had complete abortions and remaining 9 (14%) had incomplete abortions. One (1.6%) of the 63 cases complained of nausea and vomiting, and 3 (4.8%) complained of headaches. No other side effects were observed. These results suggest that ONO-802 is acceptable in the form of vaginal suppositories for the termination of early pregnancy.
Keywords:
Abortifacient AgentsAbortion, Induced--complicationsBiologyClinical ResearchContraceptionContraceptive MethodsDiarrheaEndocrine SystemEstradiol--analysisEstrogensFamily PlanningFertility Control, PostconceptionHormonesNauseaPainPhysiologyPregnancyPregnancy, First TrimesterProgestational HormonesProgesterone--analysisProstaglandins--administraction and dosageProstaglandins--side effectsReproductionResearch MethodologyVaginal SpermicidesVaginal SuppositoryVomiting