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Microcomputers in enzymology. A versatile BASIC computer program for analyzing kinetic data
Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie
|August 1, 1981
Summary
This study presents a BASIC program for microcomputers to perform regression analysis on kinetic data, offering a superior alternative to graphical methods for evaluating kinetic experiments. The program is applicable to enzyme kinetics and includes statistical methods for result examination.
Area of Science:
- Biochemistry
- Computational Chemistry
- Enzyme Kinetics
Background:
- Direct curve-fitting is the preferred method for analyzing kinetic experiments.
- Computerized numerical solutions surpass traditional graphical methods.
- Existing software often requires large computational systems, limiting accessibility.
Purpose of the Study:
- To introduce a BASIC program for desk-top microcomputers.
- To enable linear and non-linear regression analysis of kinetic data.
- To provide a tool accessible for researchers with limited computational resources.
Main Methods:
- Development of a BASIC program for microcomputer implementation.
- Application of linear and non-linear regression analysis.
- Utilization of statistical methods for critical evaluation of results.
Main Results:
- The program successfully performs regression analysis on kinetic data.
- Demonstrated applicability to common enzyme kinetics problems.
- The program is adaptable for various kinetic analyses.
Conclusions:
- The developed BASIC program offers an accessible and effective solution for kinetic data analysis on microcomputers.
- It provides a valuable tool for enzyme kinetics research.
- The inclusion of statistical methods enhances the reliability of experimental evaluations.