[Chromosomes and fertility. Translocation 13:15 and 13:18 and spontaneous abortion]

Cytogenetic investigations of three married couples, having had spontaneous abortions, was carried out, and an abnormal chromosomal complement was established in one of the spouses. The discovered balanced translocations were of the types: 13:15 (q14::q26) and 13:18 (q34:q11).--The same type of translocations 13:18 (q24:q11) was detected in two other couples. The translocation carriers are brother and sister. This aberration is inherited from one of their parents.--In the examines the balanced translocations were causes of spontaneous abortions and the birth of malformed children. According to the accessible literature data, translocations with above mentioned breaks on chromosomes have not been discovered until now.