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Related Experiment Videos

Keloids: a prospective study of 57 cases

B C Sharma

    Medical Journal of Zambia
    |June 1, 1980
    PubMed
    Summary

    This study evaluated keloid treatments, finding surgery effective for massive keloids and contractures. Ear lobule keloids respond best to specific excision and hydrocortisone, while presternal and smaller keloids benefit from corticoid injections.

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    Area of Science:

    • Dermatology
    • Surgical Oncology

    Background:

    • Keloids are benign fibroproliferative tumors resulting from abnormal wound healing.
    • Various treatment modalities exist, but optimal management strategies remain debated.

    Purpose of the Study:

    • To evaluate the efficacy of different treatment approaches for various types of keloids.
    • To determine the most effective treatments for massive, ear lobule, and presternal keloids.

    Main Methods:

    • Retrospective analysis of 57 keloid cases treated with diathermy excision and skin grafting, intramarginal excision with hydrocortisone, local corticoids, or combination therapy.
    • Specific treatment protocols were applied based on keloid size and location.

    Main Results:

    • Massive keloids and contractures required surgical intervention for functional and aesthetic improvement.
    • Ear lobule keloids showed satisfactory initial results with intramarginal excision and post-operative hydrocortisone.
    • Presternal and smaller keloids responded well to intralesional corticoid injections alone.

    Conclusions:

    • Surgical excision is indicated for massive keloids and contractures.
    • Intramarginal excision with post-operative hydrocortisone is recommended for ear lobule keloids.
    • Intralesional corticoid injections are effective for presternal and smaller keloids, though long-term follow-up is needed.

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