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Updated: Jan 26, 2026

Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins
Published on: September 23, 2021
Enhancement of relaxation rate with paramagnetic contrast agents in NMR imaging
Abstract:
Enhancement of spin-lattice relaxation using oral ferric chloride and using inhaled oxygen is illustrated. A 0.06% solution of ferric chloride reduced the spin-lattice relaxation time in the fundus of the stomach from 730 ms to 285 ms. Ferric chloride may be useful as a bowel-labeling agent. In 5 volunteers inhalation of 100% oxygen decreased the mean observed spin-lattice relaxation time of blood within the left ventricular cavity. Although the change was small, it may have important uses in monitoring metabolic processes.
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