Related Experiment Videos
Insights
Coronary artery disease (CAD) affects 26% of mitral stenosis patients over 40, particularly males with angina. Coronary arteriography is crucial for ruling out CAD in these individuals.
Area of Science:
- Cardiology
- Cardiovascular Surgery
Background:
- Mitral stenosis (MS) is a common valvular heart disease.
- Coronary artery disease (CAD) can coexist with MS, complicating diagnosis and management.
Purpose of the Study:
- To investigate the prevalence and predictors of coronary artery disease in patients with mitral stenosis.
Main Methods:
- Eighty-two patients with mitral stenosis underwent cardiac catheterization with coronary angiography.
- Statistical analysis was performed to identify correlations between clinical characteristics and CAD.
Main Results:
- Twenty-one patients (26%) had coronary artery disease.
- CAD was observed only in patients over 40 years old.
- CAD was more frequent in males with angina.
- No correlation was found between MS severity or hemodynamic parameters and CAD.
- Age, sex, and angina were correlated with CAD.
Conclusions:
- Coronary artery disease is prevalent in patients with mitral stenosis, particularly those over 40.
- Coronary arteriography is essential for diagnosing CAD in mitral stenosis patients, especially older males with angina.
- Clinical characteristics of MS do not reliably predict CAD.
Abstract:
Eighty-two patients with mitral stenosis underwent cardiac catheterization with coronary angiography. Twenty-one patients (26 percent) had coronary artery disease. Characteristics of the mitral valve area, cardiac output, pulmonary artery pressure, pulmonary vascular resistance, left ventricular end-diastolic pressure, left ventricular ejection fraction, and atypical chest pain did not correlate with findings of angina pectoris or of coronary artery disease; however, there was correlation with sex, age, and angina. Coronary artery disease occurred only after the age of 40 years and was more frequent in males with angina. Coronary artery disease could not be ruled out in patients with mitral stenosis, especially those over age 40, without coronary arteriography.