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Updated: Jul 31, 2026
06:44
Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography
Published on: April 13, 2018
Summary
Surgical ligation and stripping is a safe and effective treatment for lower limb thrombophlebitis associated with varicose veins, significantly reducing pulmonary embolism risk compared to conservative management.
Area of Science:
- Vascular Surgery
- Phlebology
Background:
- Thrombophlebitis of the lower limb is commonly linked to varicose veins.
- The introduction of anticoagulants and surgery followed reports of pulmonary embolism in superficial phlebitis.
Purpose of the Study:
- To evaluate the effectiveness of different management strategies for lower limb thrombophlebitis in patients with varicose veins.
- To compare surgical intervention with conservative treatments regarding safety and outcomes, particularly pulmonary embolism incidence.
Main Methods:
- A retrospective review of 1,000 consecutive cases of lower limb varicose veins.
- Patients with thrombophlebitis (221 cases) were categorized by management: conservative (heat/anti-inflammatories), anticoagulants, combined phlebotomy/ligation/anticoagulation, or ligation and stripping.
- Elective ligation and stripping was performed on 779 patients without phlebitis.
Main Results:
- Pulmonary embolism occurred in 10 cases (all in the conservative management group), with one fatality.
- The incidence of pulmonary embolism in the elective ligation and stripping group (without phlebitis) was 0.5%.
- Surgical ligation and stripping effectively treated thrombophlebitis and varicose veins simultaneously, with no observed pulmonary embolism in 135 treated patients.
Conclusions:
- Surgical ligation and stripping is a safe and preferred treatment for thrombophlebitis associated with varicose veins.
- The surgical approach offers simultaneous treatment of varicosities and phlebitis, requires single hospitalization, and avoids anticoagulants.
- Anticoagulants are recommended if surgery is not feasible to prevent thromboembolism.
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