Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinicopathologic studies in tympanosclerosis

K Makishima, Y Toriya, S Inoue

    The American Journal of Otology
    |January 1, 1982
    PubMed
    Summary

    Middle ear conditions like tympanosclerosis and adhesive otitis media share similar inflammatory and healing responses. A new term, tympanomastoid fibrosis, is proposed to encompass these histopathologic findings.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sign of Hard-X-Ray Pulsation from the γ-Ray Binary System LS 5039.

    Physical review letters·2020
    Same author

    Downward Terrestrial Gamma-Ray Flash Observed in a Winter Thunderstorm.

    Physical review letters·2019
    Same author

    On-ground detection of an electron-positron annihilation line from thunderclouds.

    Physical review. E·2016
    Same author

    Possible evidence for free precession of a strongly magnetized neutron star in the magnetar 4U 0142+61.

    Physical review letters·2014
    Same author

    Hardening and termination of long-duration γ rays detected prior to lightning.

    Physical review letters·2013
    Same author

    Observation of an energetic radiation burst from mountain-top thunderclouds.

    Physical review letters·2009

    Area of Science:

    • Otolaryngology
    • Pathology
    • Microbiology

    Background:

    • Tympanosclerosis, adhesive otitis media, and chronic otitis media are common middle ear conditions.
    • These conditions often present with similar inflammatory and healing histopathologic findings.

    Observation:

    • Microscopic examination of middle ear tissue revealed significant fibrosis, hyalinization, and calcification.
    • Whitish sclerotic masses, particularly around ossicular chains, were observed.
    • Longstanding middle ear effusions contribute to dense, avascular fibrous adhesions.

    Findings:

    • Histopathology indicates fibrosis of submucosal connective tissue and metaplasia of mucosal epithelium as the cause of sclerotic masses.
    • Inadequate antibiotic therapy for middle ear inflammation and effusion may lead to extensive tympanic fibrosis.

    Related Experiment Videos

  • The study observed similar inflammatory and healing patterns across various middle ear diagnoses.

    • Implications:

    • A unified diagnostic term, tympanomastoid fibrosis, is proposed to replace existing terms like tympanosclerosis and adhesive otitis media.
    • This new terminology aims to better explain the observed clinical and histopathologic conditions.
    • Understanding the role of fibrosis in middle ear pathology is crucial for effective treatment and management.