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Amebic liver abscess

S F Abuabara, J A Barrett, T Hau

    Archives of Surgery (Chicago, Ill. : 1960)
    |February 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Amebic liver abscess, a parasitic infection, is increasingly seen in non-endemic areas. Early diagnosis and treatment with metronidazole are key to managing this condition effectively.

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    Area of Science:

    • Infectious Diseases
    • Hepatology
    • Tropical Medicine

    Background:

    • Amebic liver abscess (ALA) is a serious complication of Entamoeba histolytica infection.
    • While historically associated with endemic regions, changing immigration patterns necessitate awareness in non-endemic areas.

    Purpose of the Study:

    • To analyze the clinical presentation, diagnosis, and management of amebic liver abscess.
    • To highlight the importance of considering ALA in the differential diagnosis of right upper quadrant pain and fever.

    Main Methods:

    • Retrospective case series of 35 patients diagnosed with ALA over a ten-year period.
    • Diagnostic methods included liver scan, serologic studies, abscess aspiration, and response to antiamebic therapy.

    Main Results:

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    • Most patients (32/35) had immigrated from endemic areas, but three were Chicago natives.
    • Common symptoms included right upper quadrant pain and fever; hepatomegaly was frequent.
    • Metronidazole was effective in 83% of treated patients; 9 patients required drainage for various reasons.
    • Mortality rate was 5.7%.

    Conclusions:

    • Amebic liver abscess should be considered in patients presenting with right upper quadrant pain and fever, especially those with relevant travel or immigration history.
    • Prompt diagnosis using liver scan and serologic studies, followed by appropriate antiamebic therapy, is crucial for favorable outcomes.