Effect of sodium hyaluronate on corneal wound healing

With the development of the use of sodium hyaluronate for endothelial cell protection during anterior segment surgery, we were interested in the effect of sodium hyaluronate on corneal wound healing. Therefore, the following experiment was performed. Corneal incisions were made in both eyes of 14 albino rabbits. Sodium hyaluronate was used to fill the anterior chamber of the test eye, and balanced salt solution was used in the control eye. The wounds were sutured wih 10-0 nylon. On the seventh postoperative day, and strength was measured. After suture removal, the intraocular pressure was raised until the wound burst. Results showed no statistical difference between these and control eye.