Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tuberculosis in dialysis patients

M C Belcon, E K Smith, L M Kahana

    Clinical Nephrology
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Renal stones and their medical management.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Needle Biopsy as an Aid to the Precise Diagnosis of Intrathoracic Disease.

    Canadian Medical Association journal·2010
    Same author

    Simultaneous determination of delta9-tetrahydrocannabinol and 11-nor-9-carboxy-delta9-tetrahydrocannabinol in human plasma by solid-phase extraction and gas chromatography-negative ion chemical ionization-mass spectrometry.

    Journal of analytical toxicology·2001
    Same author

    Living with lung cancer: the other side of the desk.

    Chest·2000
    Same author

    TB among aboriginal Canadians.

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2000
    Same author

    Survey of clinical veterinarians' perceptions of the potential for growth in exotic animal practice.

    Journal of the American Veterinary Medical Association·1998

    Patients with end-stage renal disease on dialysis show a tenfold higher incidence of tuberculosis. Risk factors include age, race, and immigrant status, with symptoms often mimicking renal disease.

    Area of Science:

    • Nephrology
    • Infectious Diseases
    • Public Health

    Background:

    • End-stage renal disease (ESRD) patients on dialysis may have altered immune function, increasing susceptibility to infections.
    • Tuberculosis (TB) is a significant global health concern, and its incidence in vulnerable populations requires careful monitoring.

    Purpose of the Study:

    • To investigate the incidence and clinical characteristics of active tuberculosis (TB) in a large Canadian dialysis population.
    • To identify potential risk factors and diagnostic challenges associated with TB in ESRD patients.

    Main Methods:

    • Retrospective review of data from a large Canadian dialysis unit over a 13-year period.
    • Analysis of 433 dialysis patients, identifying seven cases of active TB.

    Related Experiment Videos

    Main Results:

    • A greater than tenfold increase in TB incidence was observed in dialysis patients compared to the general population.
    • Risk factors identified included being over 40 years of age, race, and immigrant status.
    • Tuberculin skin tests were largely unhelpful; symptoms often mimicked underlying chronic renal disease; 3 of 7 patients had extrapulmonary TB.

    Conclusions:

    • ESRD patients on dialysis have a significantly elevated risk of developing tuberculosis.
    • Clinical presentation can be atypical, complicating diagnosis; early recognition and treatment are crucial.
    • Findings support previous international observations regarding TB in dialysis populations.