[Teratogenic and embryotoxic properties of drugs and alcohol]

Experiments on rats were made to study the direct and mediated action of a number of drugs (antibiotics, drugs of the phenothiazine series, prostaglandin F2alpha , partusisten, staphylococcal anatoxin) and alcohol on the development of the fetoplacental complex. The author emphasizes the necessity of a comprehensive approach to the study of the embryotoxic properties of xenobiotics with the use of the methods of in vitro cultivation of mammalian embryos and histological and histochemical examinations of the placenta and liver.