Serologically defined antigens on the surface of somatic hybrid cells

Y2C somatic cell hybrids, which immunize semiallogeneic mice and protect them against further challenge with syngeneic malignant cells, express normal H-2 antigens from parental cells and, in addition, the L antigen and the Friend, Moloney, Rauscher type-specific antigen. This was demonstrated by immunoabsorption, complement-dependent cytotoxicity and immunofluorescence experiments.