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Rapid disappearance of left ventricular mass (presumed thrombus) in a patient with cardiomyopathy

J Bensaid, P Blanc, P Virot

    British Heart Journal
    |March 1, 1982
    PubMed

    Insights

    A left ventricular thrombus resolved spontaneously in a patient with cardiomyopathy and liver insufficiency. Increased fibrinolysis, potentially aided by heparin, is the likely cause, not embolization.

    Area of Science:

    • Cardiology
    • Hematology
    • Hepatology

    Background:

    • Cardiomyopathy and hepatic insufficiency present complex clinical challenges.
    • Left ventricular thrombus formation is a known complication in certain cardiac conditions.

    Observation:

    • A 41-year-old male with diagnosed cardiomyopathy and hepatic insufficiency presented with a left ventricular mass on angiocardiography, presumed to be a thrombus.
    • A follow-up angiocardiogram five days later revealed complete resolution of the thrombus.

    Findings:

    • The spontaneous disappearance of the left ventricular thrombus suggests a hyperfibrinolytic state.
    • This is consistent with fibrinolysis observed in patients with liver cirrhosis, possibly augmented by heparin therapy.

    Implications:

    • This case highlights the potential for spontaneous thrombus resolution in the left ventricle under specific physiological conditions.
    • Understanding the role of fibrinolysis in such cases may inform future therapeutic strategies for cardiac thrombi.
    • Further research into the mechanisms of spontaneous thrombus resolution could offer novel insights into anticoagulation and thrombolysis.

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