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Related Experiment Videos

Corneal sensitivity during the menstrual cycle

B Riss, S Binder, P Riss

    The British Journal of Ophthalmology
    |February 1, 1982
    PubMed
    Summary
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    Corneal sensitivity, measured as corneal touch thresholds (CTT), increased around ovulation in women. This change in corneal sensitivity may be linked to hormonal fluctuations during the menstrual cycle.

    Area of Science:

    • Ophthalmology
    • Reproductive Endocrinology

    Background:

    • Corneal sensitivity is crucial for ocular surface health and protection.
    • Hormonal fluctuations during the menstrual cycle can influence various physiological parameters.

    Purpose of the Study:

    • To investigate the relationship between the menstrual cycle and corneal sensitivity.
    • To determine if corneal touch thresholds (CTT) change during different phases of the menstrual cycle.

    Main Methods:

    • Corneal sensitivity was assessed daily using a new Dräger aesthesiometer in 5 women with regular menstrual cycles.
    • Urinary luteinizing hormone and pregnanediol levels were monitored serially throughout one menstrual cycle.

    Main Results:

    • Corneal touch thresholds (CTT) increased in 4 women with confirmed ovulation, specifically before or on the day of ovulation.

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  • One anovulatory subject showed no change in corneal sensitivity.
  • No alterations in CTT were observed preceding menstruation.

    • Conclusions:

    • Corneal sensitivity exhibits cyclical changes related to ovulation.
    • The preovulatory estrogen peak may be associated with decreased corneal sensitivity.