Endobronchial metastatic plasmacytoma

Plasmacytomas are rare tumors and an endobronchial presentation has not been previously described. A 64-year-old white woman with metastatic involvement by plasmacytoma is presented. A review of the literature indicates the difficulty in distinguishing this lesion from benign plasma cell tumors of the lung and the prolonged follow-up often necessary to reveal metastatic behavior. Careful observation in this case led to the demonstration of metastatic lung and endobronchial lesions without the development of abnormal proteinuria or overt myeloma. The literature would suggest a key role for radiation therapy in treatment. The role of chemotherapy remains to be defined.