Acquired extrinsic pulmonic stenosis caused by mediastinal tumors

Clinically detectable pulmonic stenosis resulting from compression of the pulmonary artery or right ventricular outflow tract by mediastinal tumors is uncommon. This report describes the occurrence of pulmonic stenosis secondary to a mediastinal tumor in a patient with Hodgkin's disease and in two patients with non-Hodgkin's lymphomas. Review of 35 published reports reveals that teratomas (ten cases) and Hodgkin's disease (eight cases) are the neoplasms most frequently reported to cause extrinsic pulmonic stenosis. Chest pain and dyspnea were the symptoms most commonly reported and a pulmonic ejection murmur was the most common physical finding in patients with acquired pulmonic stenosis. The prognostic significance of acquired pulmonic stenosis. The prognostic significance of acquired pulmonic stenosis secondary to mediastinal tumors is unclear.